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This commentary examines the different types of interactions between signals that contribute to synergy at the biological level.
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Indeed, the average density of interactions between signalling modules is 6 times higher than between non-signalling PRODISTIN classes.
Thus, the combinatorial branchial arch expression of Dlx genes is achieved through interactions between signaling pathways and intrinsic cellular factors.
This simplification allows us to more focus on the interactions between signal and interference.
As knowledge from such studies accumulates, it is becoming clear that the 'cross talk' interactions between signalling systems are important features of dynamic cell regulation.
By using this functional chemical genetic screen, the authors uncovered novel interactions between signaling inhibitors that would not be predicted based on current understanding of the signaling networks.
They focused on interactions between signal crayfish and benthic fish in a British river and discovered a negative correlation between crayfish density and densities of the two most abundant fish species bullhead (Cottus gobio) and stone loach (Noemacheilus barbatulus).
Our results reveal the potential mechanism of force feedback interactions between signaling molecules on cellular membrane and viscoelastic cytoskeletal networks.
We believe that interactions between signaling pathways, so called molecular cross-talk, enables the cell to process and interpret multiple inputs differently in different contexts.
Such approaches may uncover interactions between signal transduction routes, which are to be verified in vivo.
These paths are then reduced to directed interactions between signaling molecules represented in a SIF.
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