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Nevertheless, at present it would not be possible to obtain accurate, experimentally-validated interactions belonging to expanded interaction levels in the specific context of human HF.
We found that the number of interactions between pairs of proteins that participate in the same KEGG pathway was much larger in HCS than LCS, and that LCS had more interactions belonging to the same KEGG pathways than RPS (Fig. 3C) Next, we compared the scored Drosophila PPI with two independent datasets that should be enriched for biologically relevant interactions (Fig. 4).
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These interactions belong to diverse classes.
Charge charge, charge dipole and dipole dipole interactions (Debye interactions) belong to this category as well as orientation interactions (Keesom interactions).
As all processes that are coupled by graded interactions belong to the same layer, the reduced model of the example system consists of two layers.
We investigated whether any high-impact interactions belong to those that are associated with diseases (as identified by GWAS; henceforth referred to as GWAS-genes) [ 46].
Since all of the 28 SCZ drugs involved in the 991 interactions belonged to the "nervous systems" category, we grouped the 991 interactions into 14 categories based on their interacting drugs' ATC first-level annotation.
Ingenuity Pathway Analysis (Redwood City, CA, USA) was used to determine the canonical pathways to which probesets demonstrating significant P values for "treatment response × probeset" and "medication × treatment response × probeset" interactions belonged.
The P. monticola TFs differentially expressed between compatible and incompatible interactions belong to a few superfamilies with well-characterized structural domains such as ARF2, IAA13, AP2, zinc-finger CCCH type, zinc-finger-HD, PLATZ, NAC, DOF zinc-finger, AP2/ERF-B3, R2R3-MYB, WRKY, C3HL, HD-leucine-zipper, and tubby-like F-box.
The trend that the values of K sv increased with the increasing temperature indicated that the interaction belonged to dynamic quenching [120].
spectra of mixture model compounds suggests that this polar interaction belongs to an n π* interaction between the lone pair electrons of the N-atoms in the s-triazine ring and the π*-orbital of the phenylene rings neighbouring to the sulfone linkage.
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CEO of Professional Science Editing for Scientists @ prosciediting.com