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Rotation of the wrist changes the displayed submenus and interaction with the second hand changes the displayed settings.
For the interaction with the second hydroxyl group, the residue selected to be mutated is Arg 73.
Tyr135 which is an aromatic, partially hydrophobic, amino acid was substituted to polar Asn126 in both monocot and dicot and plays a major role in the interaction with the second sulphate molecule along with Lys60 and His125 via hydrogen bonding.
Thus, the substrate is able to present the T-segment to the enzyme, even in the absence of the protein domain that normally mediates the interaction with the second DNA double helix.
However, it does not have a significant interaction with the second choice, although a secondary influence seems likely due to the high numbers of right right choices (n = 17).
The interaction with the second adenine in position six was observed only in the open state, likely due to the interaction with Asn16 which is only flipped out in the open state and thus able to contact the adenosine ring.
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The RING domain of API2 enables it to function as an E3 ubiquitin ligase, capable of auto-ubiquitination [9], [39] and ubiquitination of interacting proteins [10], [40] [42], like BCL10 via its interaction with the first BIR domain of API2 [29].
In addition, Puma may also directly interact with and activate Bax/Bak, for example, through an interaction with the first α-helix of Bax.
This, though, is in contrast to the image she projects earlier, in her interaction with the first pupil; while Lauren Worsham effectively conveys the young girl's nervousness and lack of stage presence (or "look," as Callas would have it), we don't sense in Ms. Walsh enough of the tigress that would warrant such fear and apprehension.
The Bretton Woods institutions need to be moved away from the old country-based model of interaction with the third world, and to concentrate their efforts instead on a world dominated by concerns over technology, disease and the environment.
Molecular modelling of the nuclease structure suggests that V43I substitution may lead to disposition of H4 helix, responsible for the interaction with the first base pairs of 5′end of branched DNA.
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