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Keliximab (IDEC-CE9.1, IDEC) is an IgG1 primatized macaque-human anti-CD4 monoclonal antibody, which reduces the surface density of CD4 and inhibits the CD4-HLA-II interaction to decrease the disease activity in RA [ 55].
Results of our studies with sulindac sulfide are consistent with the ROS-dependent gene repression pathway where induction of ROS disrupts miR-27a-ZBTB10 miR-27a-ZBTB10 miR-27a-ZBTB107a and interaction10 (Fig. 6).
Dietary vitamin C was also used as a continuous variable because interaction with a continuous variable refutes the possibility that dichotomizing dietary vitamin C intake might cause a spurious interaction; to decrease the skewness of the distribution, the statistical model included the logarithm of dietary vitamin C intake.
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They used the elapsed time between two consecutive interactions to decrease the screen brightness during this interval in order to have a gain in terms of the whole system energy consumption.
The pattern of the non-weighted model is for the mean variance for the smoking variable, isolated or in interactions, to decrease, except for smoking among professionals.
↑: genotype and overweight/obesity interactions to increase serum lipid levels; ↓: genotype and overweight/obesity interactions to decrease serum lipid levels; –: no interaction of genotypes and overweight/obesity on serum lipid levels.
For forced dimerization of the Cre fragments, we selected a yeast interaction domain to decrease the risk of interaction with endogenous murine coiled-coil proteins.
The co-culture of different microalgae and cyanobacteria has shown that when a more hydrophobic microorganism is co-cultured with another one presenting a more hydrophilic surface, free energy of hydrophobic interaction tends to decrease, resulting in a more hydrophobic surface.
As distances geographic, cultural, administrative/political, and economic increase, cross-border interactions tend to decrease.
One gene dosage of imp-α2 NLSB− or imp-α2 SNLSB− alleles reduced the amount of functional complexes, while imp-β KetRE34, as inferred from pulldown experiments and mitotic phenotype of the genetic interactions, appears to decrease the stability of the NLS-protein/Imp-α2/Imp-β ternary complex.
Increased interaction time led to decrease in strength in eutectoid forming and insoluble systems and improved strength in soluble systems.
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