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Celiac disease is uniquely suited to explore the effects of helminth infection; it is common [22] and remission is achieved with elimination of dietary gluten allowing host-parasite interaction to be studied free of potential artefacts caused by medications.
Elegant and seminal crystallographic studies with these purified molecules have shown that interaction with the antigenic peptide, occurs in specific regions located in the PBR called Pockets (represented by different color in Fig. 1A D), which are assumed to be relatively independent [13], [14], therefore allowing each pocket-peptide interaction to be studied separately (see Table 1).
Here, we present an improvement of the traditional intravital microscopy that allows leukocyte-endothelial cell interaction to be studied from the time the leukocyte makes its initial contact with the endothelium until it adheres to or detaches from the endothelium.
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Taguchi tables are predefined tables used to identify the individual experiments according to the number of factors and interactions to be studied and the desired resolution [5].
Split-luciferase reporters have been engineered that allow bi-molecular interactions to be studied.
The co-culture of fibroblasts and cancer cells enables direct interactions to be studied.
The static view shows us the conduits available for dynamic interactions, to be studied when the data and the computational power permit.
There is therefore a strong need for in vivo model systems that allow these interactions to be studied in detail at the cellular as well as the genomic and proteomic level.
The self-assembled monolayers present the immobilized adhesion ligand against a background that is otherwise inert and therefore allow ligand receptor interactions to be studied in the absence of other factors that can confound the experiment.
The hemolytic-negative derivative of strain W225 defective in hemolysin production and cytotoxicity [strain SM001], enabled bacterium host interactions to be studied without killing the host cells too early.
Development of an in vitro method regarding the use of ACA allows these interactions to be studied in a reliable manner that does not involve a time-consuming in vivo feeding regimen.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com