Suggestions(1)
Exact(4)
The Tondu domains of vestigial-like family member 4 (VGLL4) interact directly with YAP, thereby preventing YAP-TEAD interactions[93, 94], and a VGLL4-mimicking peptide disrupting YAP-TEAD interaction suppressed tumour growth in mice[93].
Interestingly, it was reported that blocking Shc/Grb2 interaction suppressed the growth of B104-1-1 tumours xenografted in nude mice, showing that cancer treatment might also target the adapter proteins.
In a head and neck carcinoma model, α5β1 integrin engagement with fibronectin matrix promoted tumour cell proliferation, whereas disruption of this ECM interaction suppressed extracellular signal-regulated kinase activation and induced a dormant-like state [ 46, 47].
In HCC, HBV may confer the development of HCC via octameric tandem repeats that can bind on PARP-1, and this interaction suppressed the DNA repair activity of PARP-1 and even increased the replication efficiency of HBV [ 156].
Similar(55)
We also confirm its association with the tumour suppressor p53 as indicated by other researchers [13], [14] and show that this interaction suppresses the DNA binding activity of BRCA1.
Recently, it was demonstrated that SLIT2-ROBO1 interaction suppresses the activity of CDC42 [ 58].
Our results suggest that Dll1/Notch2 interaction promotes osteoclastogenesis, whereas Jagged1/Notch1 interaction suppresses it in both mice and humans.
These results suggest that Notch2/Dll1 interaction promotes the differentiation of osteoclasts while Notch1/Jagged1 interaction suppresses it in both mice and humans.
Age x gender interactions suppressed.
We first asked whether disrupting microtubule kinetochore interactions suppresses the kinetochore localization defect of monopolin in CUP-CLB3 cells.
10.7554/eLife.00117.029 Figure 5. Transient disruption of microtubule kinetochore interactions suppresses the chromosome segregation defects in CUP-CLB3 cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com