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These results will be useful to the structural study of oxidized and reduced Grx2 and the interaction study with MsrA.
Three moieties (pyridine, heptylamine and quinaldine) which are liquid in room temperature are chosen for the interaction study with Na-montmorillonite.
An interaction study with P. arrhenomanes and the migratory ectoparasitic nematode Tylenchorhynchus annulatus showed a significantly decreased reproduction rate of the nematode when co-inoculated with a high oomycete inoculum (Bond et al. 2004), revealing that this antagonism is not only limited to sedentary nematodes.
The same study protocol was followed for Lepidium sativum and CsA interaction study, with a difference of Lepidium sativum (150 mg/kg p.o). which was administered orally in place of Nigella sativa (200 mg/kg, p.o).
However, evidence against inhibition of CYP3A4 activity by R115777 was observed in a previous interaction study with another CYP3A4 substrate, docetaxel; single-dose administration of R115777 (200 or 300 mg) was shown to have little effect on the systemic exposure to docetaxel.
Evidence from a combination of five phase I/IIa double-blind, placebo-controlled, multiple-dose studies with maraviroc alone, and one drug drug interaction study with oral contraceptives, in a total of 195 individuals including 66 HIV-infected patients have demonstrated that maraviroc is well tolerated at doses up to 300 mg twice daily (McHale et al. 2005).
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Protein interaction studies with nem1 have identified three interacting partners (nup84, nup85, nup120), all components of the yeast nuclear pore complex (NPC) [ 33].
The underlying reasons have been elucidated by structural and interaction studies with the help of DSC, SCXRD, vibrational and multi-nuclear NMR spectroscopic techniques.
These in silico predictions were compared to in vitro interaction studies with Ras and MST kinase (a SARAH domain-containing protein).
We show the high potential for metabolic interaction studies with the membrane reactor and discuss about the possibility of the defined co-culture for propionic acid production in a CSTR process.
Knowledge of 3D structure of GKLdv is essential for elucidating interaction studies with the inhibitors and compared with substrate binding pattern in both the built model and template structures.
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