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Exact(13)
The fact that our model can only explain the part of the interaction preference among proteins of a similar age that is caused by interacting paralogs, suggests that future work should be directed at identification of additional important factors.
We investigated relative preferential interaction of Na+ and K+ with carboxylate-functionalized silver nanoparticles (carboxylate AgNPs) to determine if interaction preference followed the Hofmeister series (Na+ > K+).
The profile represents the current older person's interaction requirements and these can be changed at any time to take into account a change of interaction preference or underlying interaction requirements relating to old age.
However, using a formal test of interaction, preference was not associated with outcome.
Even though protein age correlates with the rate of sequence evolution, the latter is not the determining factor in the interaction preference among proteins of a similar age.
The results described above demonstrate that gene duplications contribute strongly to the observed interaction preference among proteins of a similar age.
Similar(47)
Scoring methods based on sequence and/or structure can predict interaction preferences in coiled-coil-mediated bZIP transcription factor dimerization.
These statements are thought to support the underlying flexibility to personalise the interaction method based on the older person's current interaction requirements and personal interaction preferences.
In protein structure prediction, there is still much interest in using amino acid interaction preferences to align (thread) a protein sequence to a known structural motif.
Their sub-junctions also resemble local helical configurations found in three- and four-way junctions and are stabilized by similar long-range interaction preferences such as A-minor interactions.
We present a model for predicting the interaction preferences of coiled coil peptides derived from bZIP transcription factors that performs very well when tested against experimental protein microarray data.
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