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It has been found from this investigation that the crack growth rate is enhanced significantly through load interaction of the variable amplitude fatigue.
Fig. 4 shows the complex interaction of the variable factors.
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The interaction of the variables "time and treatment" was not significant (P = 0.022).
The response surface curves are plotted to explain the interaction of the variables and to determine the optimum level of each variable to reach a maximum response.
Since the interaction of the variables was significant, one-way ANOVA and Tukey's HSD test were used to assess the effect of each variable.
The correlation of the involved parameters was examined by employing the Central Composite Design (CCD) method through designating set up experiments that will determine the interaction of the variables.
*RMANCOVA analysis for the interaction of the variables treatment group and length of treatment.
5-HIAA levels had significant effects on the interaction of the variables MDMA dose × WIN dose [F 4,44) = 3.271; p < 0.01].
In the hippocampus, serotonin concentration had significant effects on the interaction of the variables MDMA dose × WIN dose [F 4,46) = 2.828; p < 0.03].
We checked the interaction of the variables with each other and with time to event (time of death or censoring time) to find those variables with a time-varying effect on the risk of mortality.
Finally, we investigated differences by sex by including the interaction of this variable with the contaminants in the main analyses.
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