A simple method of estimating the effect of inhomogeneity interactions on the overall properties (elastic and conductive) is developed.
We show that these buried polar residues often span elements of secondary structure and provide stabilizing interactions of the overall protein architecture.
The vast amount of genes and proteins that participate in biological networks imposes the need for determination of protein complexes within the network in order to reduce the complexity, while these complexes will be the first step in deciphering the composite genetic or cellular interactions of the overall network.
This study reveals the influence of partial interaction to the overall performance and the proposed value for the two factors is of great significance in simplifying the design procedure of BSP beams.
The contribution of interactions to the overall variation ('N × G' and 'GS × G') was usually small and non-significant in all the N parameters measured.
When adding the feature parameter of motif frequency to amino acid composition and interaction of segments, the overall accuracy increased to 76.25%, an 8% higher overall accuracy.
After adding the feature parameter based on the interaction of segments, the overall accuracy increased to 68.80% (a 25% higher overall accuracy).
The interaction terms of the overall employment rate and the benefit replacement ration (BRR) are negative for youths and positive for young adults and adults 25-344 and 45-54), though only the coefficient for young adult is statistically significant.
The importance of this interaction in the overall function of DNase I, especially with respect to removal of potentially immunogenic chromatin complexes in vivo, remain to be confirmed, and it is possible that other related serine proteases may also mediate this process.
Multivalency and particularly heteromultivalency attempts to unite at least two separate targeting moieties that will not only be additive but may synergize either by allowing increased avidity to the overall cellular or tissue target or by enabling a statistically greater likelihood of interaction with the overall target.
