Sentence examples for interaction of the compound from inspiring English sources

In the latter mechanism, antiprion drugs are not expected to interact directly with the prion proteins whereas the former mechanism implies direct interaction of the compound with the prion proteins either in their normal or prion form.

The existence of shoulder might be due to the interaction of the compound with the protic solvent used.

Docking studies were performed to model the binding interaction of the compound 26m with the SARS-CoV 3CL protease.

UV Vis spectroscopic result reveals that the binding mode of interaction of the compound with SS-DNA is intercalative DNA interaction and the intercalative mode of interaction was further supported by viscometry.

Taken together, these data suggest indirect inhibition of the viral polymerase complex through interaction of the compound with a cellular cofactor required for RdRp activity as the basis for the antiviral effect of JMN3-003.

This suggested to us that a molecular interaction of the compound with misfolded proteins could be occurring in vivo.

This suggests that the interaction of the compounds with the soil was mainly hydrophobic interactions.

This was done by analyzing the interaction of the compounds 4a with the active sites of spinach KARI.

The binding interaction of the compounds was found to be approximately 102 M−1, with that of the most potent compound 1- 2-dimethylaminoethylamino -9(1- 2-dimethylaminoethylamino -9

Binding studies indicated that the S configuration at the 3-C position of the piperidine ring is crucial for an optimal interaction of the compounds at all three α1-AR subtypes.

The interaction of the compounds with calf thymus DNA (CT-DNA) was investigated by absorption, emission titration, electrochemical and viscosity methods, indicating that the ligand and the complexes interacted with CT-DNA through intercalation.