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In the setting of transcriptional regulation, there are a host of regulatory architectures both in prokaryotes and eukaryotes which require the interaction of sequences on the DNA that are not adjacent [4] [7].
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The results revealed a main effect of block (F 3,219) = 63.61, p <.001), no effect of the sequence (F 5,73) = 1.71, ns) and no significant interaction of sequence with block (F(15,219) = 1.59, ns), demonstrating that the pseudorandom ordering did not affect individual contribution levels in each block.
Despite the relatively numerous reports concerning the docking interaction between MAPKs and specific peptides, there are no structural analyses extended to the interactions of sequences proximal to the KIM region as well as to those involving the kinase active sites.
Perhaps berenil negatively influences transcription by preventing upstream sequences from interacting with nucleosomes and positively affects transcription by facilitating the interaction of upstream sequences with nucleosomes.
To explore the biophysical mechanism underlying such transitions we use a three-letter continuous protein model with seven atoms per amino acid to provide realistic sequence-structure and sequence-function mappings through explicit simulation of the folding and interaction of model sequences.
Since these processes involve the interaction of repetitive sequences, the frequencies of UCO and GC decline with physical distance and sequence dissimilarity [ 60, 61], which is corroborated by the paucity of EGC here.
The interaction of upstream sequences with the protease domain was not able to initiate this process.
The processes that regulate the rate of mRNA decay are complex and involve the interaction of regulatory sequences within the mRNAs themselves with proteins and noncoding RNAs such as microRNAs (miRNAs).
PBM is capable of analyzing the interaction of a sequence-specific TF with tens of thousands of short DNA sequences (probes) in a single experiment, and thus provides a highly detailed picture of TF-DNA interactions.
When Aggie first saw the show I could tell she was frustrated by the different opening, but this time – instead of squirming and asking "Where's Biff?" a million times – she enjoyed the audience interaction of this sequence, especially when Miss Polly gets the kids to wiggle their fingers and point their toes.
The basic assumption is that many putative binding sites, including the sites of TFexp and of other factors, not just the single best match, may contribute to interaction of this sequence to TFexp.
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CEO of Professional Science Editing for Scientists @ prosciediting.com