Sentence examples for interaction of genetic variations from inspiring English sources

Interestingly, a three-way interaction of genetic variations, DNA methylation and environmental exposure was first demonstrated by Salam et al. [ 25], who showed that exposure to particulate matter and methylation levels of the NOS2 promoter haplotypes jointly influenced levels of exhaled nitric oxide.

This study represents the first report of an interaction of genetic variation and DNA-M of GATA3 on the risk for asthma at 18 years, which is modified by the use of OCP and age at menarche.

With the exception of rare monogenic disorders, most type 2 diabetes results from the interaction of genetic variation at multiple different chromosomal sites with environmentalexposures experienced throughout thelifespan (1).

Moreover, it is likely that interactions of genetic variations with environmental factors are required to trigger major mood disorders.

The vitamin D receptor gene (VDR) was selected, and the interactions of genetic variation in VDR with circulating vitamin D levels and gemcitabine treatment were evaluated.

Additional work has been done on candidate genes, i.e., genes chosen a priori and not through a genome scanning studies, including several studies of CNTNAP2 and some recent work implicating BDNF as a gene x gene interaction partner of genetic variation on chromosome 13 that influences language.

It is possible that the interaction effects of genetic variation and stress on depression are moderated by gender, perhaps due to the influence of gender differences in hormone levels on gene expression, serotonergic function, and neural development.

While environmental (non-genetic) risk factors for the disease are well established, the role of genetic variations and gene environment interactions remain understudied in this population.

They have a lot of genetic variations".

Their database is able to explain how hundreds of millions of genetic variations can impact a genetic code.

The customary partitioning involves: 1) Differences among environments in the ranking of genotypes (RC interaction)   2) Variation among environments in the expression of genetic variation (LoE interaction)  .