Exact(2)
This mapping was performed because it is not uncommon that a particular isoform is annotated as the interacting protein, even when the interaction is not specific to that isoform.
This interaction is not specific to Smc4 or Cap-H2 mutant alleles and therefore is also unlikely to be due to nonspecific genetic background effects in the condensin mutant lines.
Similar(58)
The band-shift also observed in DKzeo cells (data not shown), indicating that this interaction was not specific for HEK293 cells.
However, molecular recognition based on chemical interfaces relying on weak interactions is not specific enough to produce unique response pattern even in an array format.
To confirm that these genetic interactions were not specific to the rsp5-1 another alleler allele, rsp5-326 [35] was tested (Figure 2B).
Similar perturbations on Spt16-chromatin association by the H4-R36A and H4-K31E mutants were also seen at FBA1, another constitutively expressed gene, showing that the effects of these histone H4 mutants on Spt16−chromatin interactions are not specific for the PMA1 gene but are likely to be more widespread.
The observation that PRG4 + HA friction reduction is not disrupted by the cross-linking procedure is consistent with previous evidence suggesting that the PRG4 + HA interaction is not a specific site-dependent binding, but rather a physical interaction [ 12, 39].
We observed that loss of hecd-1 suppresses the sterility associated with loss of glp-1, indicating that the interaction is not allele-specific.
The observed interaction between EC HSPGs and CXCL12α is not specific to RA ECs, because it has been reported in other human ECs such as primary or transformed HUVECs [ 17, 19].
Consistently, in HCC cells, such interaction was also detected, indicating that this interaction is not cell type specific (Fig. 3A and 3B).
However, HflX-50S interaction is not limited to a specific nucleotide-bound state of the protein, and the presence of any of the nucleotides GTP/GDP/ATP/ADP is sufficient.
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