Sentence examples for interaction is instrumental from inspiring English sources

Co-immunoprecipitation experiments suggest that WRN and RPA association is enhanced in response to fork blockage inducing-treatments and this interaction is instrumental for the WRN-mediated displacement of RPA from DNA that contributes to fork recovery [ 23].

As neither Gln121 nor Gln42 are conserved amongst the wider NCS1 family, it seems unlikely that this latter interaction is instrumental in inducing the conformational changes necessary for switching the transporter from outward to inward facing, or indeed other conformational changes, such as inward to outward facing.

Our findings reveal a novel regulatory event that is essential for accurate meiosis I chromosome segregation and demonstrate that temporal restriction of microtubule kinetochore interactions is instrumental in transforming mitosis into meiosis.

Such casual interactions are instrumental in cultivating innovative ideas and building respectful, collegial relationships that persist throughout a career.

Collectively, they reemphasize the notion that exposed, hydrophobic IDP residues function as key aggregation determinants and that aromatic π π stacking interactions are instrumental for fibril formation, thereby offering clues for therapeutic intervention.

Finally, we have shown that excitatory and inhibitory interactions are instrumental for changing the strength and the time delay in the coupling among neurons, resulting in different (collective) behavioral periods.

Interaction of such factors is instrumental in shaping fisher migration as an activity into an important livelihood strategy.

Because the cue domain of gp78 is instrumental for interaction with htt, we next examined whether an intact cue domain is required for Nhtt138Q degradation.

Provider interaction in large physician groups is instrumental to quality improvement [ 42], but is rarely seen in dentistry [ 43]; as a result, dental quality initiatives are limited in number and scope and not widely reported in the literature [ 44- 47].

This is supported by reports that Uhrf1 interacts with Dnmt1 through the RFTS domain [98], and this interaction may be instrumental in relieving the autoinhibitory effect on Dnmt1, making it competent for DNA methylation.

The interaction between Nur 77 and Bcl-2 is instrumental in the induction of apoptosis during negative selection of autoreactive thymocytes [34].