Sentence examples for interaction is disrupted from inspiring English sources

Although CPAP and STIL are known to bind each other, how they interact on a molecular level to form centrioles and how this interaction is disrupted in microcephaly is not well understood.

It interacts with the region encoded by exon 2b [78] and the SMN-Gemin2 interaction is disrupted by competition with an N-terminal SMN peptide aa13-444) or in the absence of the SMN N-terminus (Δ1-39) [73], [82].

In contrast, the control molecule, S*, appears as a very different, open geometry because the KL interaction is disrupted.

To establish whether the degree of information transfer during social interaction is disrupted in GF mice, performance in the social transmission of food preference test was assessed.

These mutants potentially would be predicted to be phenocopies of one another, because in both cases, the sclerostin Lrp5 interaction is disrupted.

Altogether, these data identified the III-IV linker region of Cav3.2 as the channel region engaged in the interaction with calnexin C-tail, and indicate that this interaction is disrupted by the GAERS Cav3.2 missense mutation.

Overexpression of p62 has been shown to reduce TDP-43 aggregation in both an autophagy- and proteasome-dependent manner (159) Moreover, p62 directly interacts with TDP-43 and this interaction was disrupted in FTLD brains (160).

Under oxidative stress conditions, Trx-AIF interaction was disrupted.

To show the importance of the KL interactions, a control molecule (T4*) was prepared, in which a pair of KL interaction was disrupted by sequence mutation.

A sequential ChIP experiment was done to test whether the CARM1/GRIP1 interaction was disrupted by iAs.

Briefly, the first antibody-antigen interaction was disrupted by adding 10 mM DTT, final concentration.