However, modeling the arrestin rhodopsin interaction is challenging because of the extremely flexible nature of the arrestin loops.
As shown in Figure 4c, only ROCK1, but not RhoA, had an interaction with GST-Erk2, and this interaction was challenged by selenite treatment as the activity of ROCK1 was decreased.
Dispersibility of graphene sheets in polymer matrices and interfacial interaction are challenging for producing graphene-based high performance polymer nanocomposites.
But the complexity of ECM and cell ECM interactions is challenging.
Measuring such colloidal interactions is challenging given that they are weak and potentially involve diverse target molecules.
Nonetheless, predicting the impacts of novel interactions is challenging, partly because many methods of inference are contingent on the current configuration of climatic variables and species distributions.
The variation of conductor voltage current characteristic as a result of cable electromagnetic, mechanical and thermal interactions is challenging to model.
Following the complexity of protein-ligand interactions and fully characterizing by experimental means its effects on the protein-protein interactions is challenging.
Although an improved understanding of how germline genetic variants interact with other cancer risk factors may allow better prevention and treatment of human cancer, measuring and quantifying these interactions is challenging.
Studying such interactions is challenging, owing to the relatively small magnitude of the anticipated interaction effects and the difficulty in accurately and precisely quantifying lifestyle behaviors.
Inhibitors for protein protein interactions are challenging to design, in part due to the unique and complex architectures of each protein's interaction domain.
