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In fact, several studies highlighted an important role for EphA2-ephrinA1 and EphB4-ephrinB2 interaction in tumor angiogenesis [7].
The data indicate a new mechanism of thrombin interaction in tumor cell metastasis that is nonproteolytic.
Such studies are needed to ultimately reveal the functional consequences of P-selectin/ligand interaction in tumor progression, making specific links between platelets and tumor metastasis.
Destabilization of the HSP90-p23 intumortion in tumor cells and the subsequent measurement using immunoprecipitation therefore can be used to monitor the effect of HSP90 inhibitors on the HSP90 catalytic cycle.
Paradoxically, the up-regulation of PDGFD in CIKIL-15 not only could promote the proliferation of CIKIL-15 cells but also promote tumor cells survival through cell and cell interaction in tumor cytotoxic assay.
Obviously, the role of Qa-1 NKG2A Qa-1 NKG2An interactionmuniny in immunocompetumorhosts immunitycomplinated, as we were surprimmunocompetentared to wild-type animals, metastasis of B16 melanoma cells in Qa-1 knockout mice was dramatically enhostsd (data not shown).
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Since traditional polyethylene glycol (PEG) surface layer interferes with the cell-NP interaction in tumors, we used a water-soluble and blood-compatible chitosan derivative called zwitterionic chitosan (ZWC) as an alternative surface coating for poly(lactic-co-glycolic acid) (PLGA) NPs.
The miR-107 negatively regulates the miRNA let-7 via direct interaction in tumors and in cancer cell line.
Sutherland, R. Cell and environment interactions in tumor microregions: the multicell spheroid model.
Altogether, these data suggest a significant role for tumor cell elastin interactions in tumor progression.
Abnormal mural cell interactions in tumor vasculature contribute to the presence of non-perfused vessels, aberrant vessel size, loss of the hierarchical vessel organization and sensitivity to anti-angiogenic agents [11].
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