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We compute the mean interaction frequency for all intra- and inter-domain interactions at various genomic lengths and plot the distribution of means for multiple resolutions).
We further computed chromosomal interaction frequency for every 1 Mb region based on the Z-score, i.e. the number of non-zero Z-scores in the region divided by the total number of 1 Mb regions in the human genome (Table 1).
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Interaction frequencies for Kcnq1 and Kcnq1ot1 were normalized to a control interaction at the H19 locus to allow comparisons between different tissues and cell types.
Considering the size of the operons and genes, the genome was divided into 10-kb bins, and the interaction frequencies for restriction fragments were assigned to the corresponding bins [ 12]. f ij is the interaction frequency between bin i and bin j.
Interaction frequency was also higher for pairs of species with a higher product of their abundance and higher temporal overlap, with the exception of S. melanocephala (Fig. 2).
For example, interaction frequency between workers in service jobs and clients/customers is significantly higher than for employees in managerial posts and so thus may only reflect differences in positions and even the higher frequency-associated disadvantages in job characteristics.
After preliminary testing of JSNET2009 data, it is found that, after controlling for profession, interaction frequency with clients/customers has a significant negative correlation to incomes and job levels (among other factors) of workers.
In this manner, we obtained the interaction frequency between any two SOCs for 23 SOCs involved in the AA network.
We found that under the same cutoff value for chromosomal interaction frequency, the number of interactions at E2-treated condition was less than that in the control condition.
The results suggest that the overall chromosome interaction frequency and pattern are changed for all chromosomes (i.e. Figure 2, chromosome 20, the intra-chromosomal interaction frequency and pattern are clearly changed before and after E2 treatment).
The three-way interaction results also suggest that interaction frequency is the most important dimension for increasing creativity by creating both knowledge sharing and a co-operative culture in the learning environment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com