checked ∼450 protein– protein interaction facts, which is a limited sample from which to infer the accuracy of all biocuration (see Discussion for other related literature).
Also, the true relevance of some drug drug interactions identified by Drugs Interaction Facts software or the additional manual search may sometimes be questioned (e.g., NSAIDs and bisphosphonates or NSAIDs and SSRIs).
Here, we have provided evidence for the physical and functional interaction of FACT with Pol I complexes, as well as a physiological role for FACT in rRNA gene expression regulation in cells.
This has become my family, and I've always loved the interaction, the fact that people here would come up and talk, and kids would hug me on the street, and to them I was just David".
There is a need, therefore, for a broader interpretation of the role of institutions that extends beyond a piecemeal study of economic, social and political institutions; their interaction, in fact, is crucial to understanding the influence they have.
However, the lunar interaction in fact has a number of surprisingly complicated aspects (Halekas et al., 2010b), some with effects that may propagate well upstream from the lunar surface.
Thus, in presence of radiative interaction, in fact, even very remote QDs cannot be considered as isolated systems, and the QD ensemble is expected to develop signatures of cooperative radiation or superradiation [15].
Proceeding to explore the influence of Glob's tome, she noted that many artists and writers had used it as a basis for learning more about the bog bodies, to whom their works were dedicated, and that Glob himself had successfully blended an engaging narrative with archaeological information, and that he was "profoundly influenced by the potentiality of interaction between fact and fiction".
Particular attention has been given to the protein-protein interactions, in fact we have chosen several interaction data sources for yeast and human proteins, such as Mint [ 27], Intact [ 28], Bind [ 29] and BioGrid [ 30], in order to retrieve the interactors for each protein stored in the database for a better understanding of the cell cycle interaction network.
There appears to be no simple dependence between protein evolution rate and the number of protein-protein interactions; in fact, the slight negative correlation between the number of interactions and the evolutionary rates is no longer statistically significant with the corrected data.
Other studies have supported a mechanism that involves specific interactions between FACT and H2A-H2B dimers as central drivers for alterations in DNA-histone interactions conducive to transcription elongation (Winkler et al. 2011; Hondele et al. 2013; Hsieh et al. 2013).
