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The "interaction export" interface allows the query and download of interactions from different publications for a set of either DNA baits or TFs.
Additionally, the home page links to an "interaction export" page and to an "export all interactions" tool that allow query and download of all or a subset of interactions.
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The COMMD domain is important for protein-protein interactions, nuclear export and postranslational modifications of COMMD proteins [3] [5].
This IcmF-associated (IAHP) cluster has been associated with mediation of host interactions, via export of effector proteins that lack signal sequences [ 53].
The exit of the nascent chain out of the ribosome tunnel is often coupled to various modifications and interactions with export targeting particles (i.e., signal recognition particle), chaperones and/or folding catalysts [ 4– 6].
A visualization application is therefore needed that: can be easily accessed from within a web server to display its results; operates as a standalone application; is platform-independent and free of external dependencies; enables user-interaction; and exports publication-quality pictures of edited/displayed RNA structures.
Post-stress, de-phosphorylation of N17 would presumably be required to allow CRM1 interaction, hence nuclear export and the restoration of huntingtin nuclear levels to steady state.
This interaction causes nuclear export and degradation of BCL6 and might result in the downregulation of BCL6 repressor activity for the cyclin D2 promoter in gastric cancer cells.
The identified interaction between nuclear export and nuclear de-phosphorylation is novel, and the obtained behaviour was unpredicted; the insensitivity to the rate of JAK phosphorylation is another interesting outcome.
We also identify physical and functional interactions between Ccr4-Not subunits and multiple NPC components, and implicate these interactions in mRNA export.
The Rev-mRNA complex is then exported to the cytoplasm by interaction of the nuclear export signal (NES) of Rev with CRM1 (or exportin 1), a component of the cellular nuclear export machinery [7] [10].
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