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The Y2H data were isolated from downloads of the BioGRID Interaction Database, Database for Interacting Proteins (DIP), IntAct database, and Molecular INTeraction Database (MINT) [ 52- 59], yielding 29096 unique interactions from 1680 publications.
Using two interaction databases (iPfam and the human interaction database), a total of 1456 possible human interacting partners were identified.
Gao, N.L. et al. MVP: a microbe-phage interaction database.
Schaefer, C. F. et al. PID: the Pathway Interaction Database.
Kamburov, A., Stelzl, U., Lehrach, H. & Herwig, R. The ConsensusPathDB interaction database: 2013 update.
Chatr-Aryamontri, A. et al. The biogrid interaction database: 2013 update.
Ceol, A. et al. Mint, the molecular interaction database: 2009 update.
Kerrien, S. et al. The intact molecular interaction database in 2012.
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BIND is the world's largest biomolecular-interaction database.
The NCBI HIV-Human Protein Interaction database is used to construct a protein interaction network.
www.pharmgkb.org Drug Gene Interaction Database (DGIdb) Database and web tool for mining over 14,000 drug-gene relationships.
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