Exact(1)
Creation of DSBs elicits two general repair responses in eukaryotic systems [10], [11], [12], [13], [14]; HR, which requires interaction between sequences at or near the break and homologous sequences lying on a sister-chromatid, homolog or non-homologous chromosome, and non-homologous end-joining (NHEJ), which utilizes minimal or no homology to bring together the ends of broken DNA molecules.
Similar(59)
There was no significant interaction between sequence and the results of the Bruce tests (P = 0.851).
The mouse Xm brain and XX brain libraries represent the libraries sequenced with the lowest depth of coverage in our RNA-seq data collection, suggesting an interaction between sequence coverage and the analysis of global gene expression (discussed below).
In those cases, interactions between sequences have to be controlled to avoid undesirable reactions.
Previous results with metazoan exons indicated that RNA base-pairing interactions between sequences flanking an exon can enhance circle formation.
The observation that HBP/SLBPΔE2+ΔE3 protein lacking exon 2 sequence in addition to exon 3 is found in the nucleus and cytoplasm suggests that there may be complex interactions between sequences in this region of the protein which are important for cellular localization.
The functional topology of sequence space depends strongly on the degree and type of epistasis, defined as genetic interactions between sequence sites, such that the effect of a mutation at one site depends on the state at others.
However, these earlier classical studies were unable to capture the three dimensional (3D) spatial organization or the temporal dynamics of the functional interactions between sequence-specific transcription factors (TFs) and distal enhancers.
We have tested the hypothesis that activation of BCR-ABL may involve direct interaction between BCR sequences and the tyrosine kinase regulatory domains of ABL.
It was shown that secondary structure interaction between two sequence segments located downstream of the 5' splice site and upstream of the branchpoint sequence promotes efficient splicing of the RPS17B pre-mRNA [ 7].
The further interaction between G4 sequence of the signal probe and hemin generated a G4 hemin complex, which catalyzed the electrochemical reduction of hydrogen peroxide, producing amplified readout signals for Hg2+ interaction events.
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