mFR data revealed a significant interaction between force and CNTF genotype.
This model defines a system of nonlinear ordinary differential equations to simulate the interaction between force, the intracellular Ca2+ handling, and sarcomere length.
The larger the forces the steeper increase of skewness (for all tests together: effect of time P < 0.001; interaction between force and time P = 0.005; effect of time in unloaded test P = n.s.; for the tests 5, 10 and 20% MVC interaction between force and time P < 0.001).
During all the dynamic tests the CV significantly declined (effects of time for the unloaded test P < 0.02; for other tests P < 0.001), whereby the decline was steeper with larger forces (interaction between force and time, P < 0.001).
During the tests the SD-PV changed significantly with time, depending on the force level (for all tests effect of time P = 0.011, interaction between force and time P < 0.001).
We emphasize that these dynamics result from an interaction between forcing the system with the changes induced by the vaccine program, and the dynamical structure of systems with multiple attractors.
But during the 20% MVC test the PF significantly diminished, at the beginning gradually and from about 120 s steeply (interaction between force and time for all the four tests, P < 0.001; for the three lowest force levels, P = 0.234; effect of time for the three lowest force levels P = 0.541; effect of time for 20% MVC P < 0.001).
In the three lower force levels, the SD-PV first declined over about 90 s and then stabilized (interaction between force and time over 0 240 s P = n.s.; effect of time over the time windows 0 60 s P < 0.001, 60 120 s P = 0.075; 120–180 and 180 240 s for both P > 0.343).
