Here we show that, upon mitophagy induction, AMBRA1 binds the autophagosome adapter LC3 through a LIR (LC3 interacting region) motif, this interaction being crucial for regulating both canonical PARKIN-dependent and -independent mitochondrial clearance.
The discs are thought to resist compressive forces by their high content of the proteoglycan aggrecan, which interacts with hyaluronate to produce large proteoglycan aggregates, with each interaction being stabilized by the further interaction of a link protein [ 5, 6].
The N-terminal fragment of UvrD, which contained domains 1a and 1b, interacted with all three UvrB fragments tested, with the strongest interaction being made with UvrB domains 1b and 3.
Most DNA polymerases interact with their cognate processive replication factor through a small peptide, this interaction being absolutely required for their function in vivo.
Thus, one state erects a tariff barrier to protect its industry against the competition of a trade partner, and the partner retaliates, the retaliatory interaction being repeated until the two countries find themselves in a trade war.
1. Molecule-substrate interaction being stronger than molecule-molecule interaction.
Molecule-substrate interaction being equal to or weaker than molecule-molecule interaction. .
The model includes the fibre/matrix morphology, with the interface interaction being governed by the Coulomb friction law.
Nevertheless, when it is combined with a peripheral MAO-A inhibitor (like harmine), its oral biodisponibility increases, this interaction being the base of ayahuasca psychotropic effect (McKenna 2004).
These sidebands are residual signals from 1H-1H dipolar coupling, this interaction being strongly averaged by the fast magic angle spinning in the present experiments.
The study finds that inter-firm network initiatives have faced a number of problems, resulting in the level of inter-firm interaction being generally fairly low and unintensive.
