Responses do differ, however, for the social interaction and interests and psychomotor retardation items.
However, responses for the social interaction and interests and psychomotor retardation items did differ.
The self- and clinician-administered versions of the HAM-D6 measure depressed mood, self-esteem and guilt, social interaction and interests, psychomotor retardation, anxiety, and somatic symptoms.
Furthermore, the intra-correlation coefficient for the psychomotor retardation was found to be very low, but for the social interaction and interests item, an adequate correlation emerged.
This HAM-D6 is composed of items measuring core symptoms of depression (i.e., depressed mood, self-esteem and feelings of guilt, social interaction and interests, psychomotor retardation, anxiety, and somatic symptoms).
ICC values were within adequate parameters for items 1 3 (depressed mood, self-esteem and guilt, social interaction and interests), low for items 5 6 (anxiety, somatic symptoms), but very low for item 4 (psychomotor retardation).
A Social Interaction Deviance Composite score can also be derived from the discrepancy between measures of the structural and pragmatic aspects of language, combined with the two scales concerned with social interaction and interests.
In English, the second response option for the social interaction and interests item reads: "I have felt that I have had difficulty performing my daily activities, but I was still able to perform them with great effort".
It said: "Despite a strong level of interaction with and interest from institutional investors, the company and its majority shareholder have decided to discontinue its plans for an IPO at this stage.
Clinical trials have demonstrated that donepezil enhances AD patients' social interaction, engagement and interest [ 51].
