When stratifying smoking status into never, past, or current (table 6), there was little evidence for interactions except a modest additive interaction between past smoking and HLA-SE for seropositive RA (p = 0.04).
While statistical software such as nQuery Advisor and SAS can handle power and sample size calculations for detecting interaction effects, a modest body of literature exists describing the effect of the magnitude of the interaction effect and distribution of the prognostic factor have on power and sample size.
However, changes in outer coordination sphere interactions lead to a modest decrease in the relative occupancy of the low and high pH modes.
We did observe a modest interaction between BMI and rs8050136 (FTO) (uncorrected interaction p value = 0.03).
Finally, there was a modest interaction between the bin values of the more contemporary movies (1990 2015) and those of these midrange movies (1960 1985; F[11,996]96] = 5.32, p = .02).02
Our simulations contained a modest interaction effect (h2 = 0.05) in the presence of very small main effects (h2 = 0.01) at each of the interacting genetic variants.
There is a modest interaction between the UVB index and lung cancer for males, which could affect the multiple linear regression results.
Lastly, DSL exhibited a strong binding preference for kidney hGGT1 and a modest interaction with liver hGGT1, yet this lectin exhibited no apparent affinity for Pichia pastoris-expressed hGGT1.
Results exhibited a modest interaction of age on the association between APOE ε4 and cognitive function in the oldest population (Q3-Q5) (OR using unadjusted model = 0.89, 95% CI = 0.81-0.99, p = 0.03; OR using fully adjusted model = 0.90, 95% CI 0.80-1.01; p = 0.08) (Additional file 1: Table S4).
In previously published analyses, a modest interaction was observed for the outcome of total mortality between the intensive glycemia and BP interventions (P = 0.03); the group that received both intensive interventions had the highest mortality, while the groups receiving either or both standard interventions had lower mortality (Supplemental Fig. 4 in 11).
