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In general, protein domains exposed on the surface of viruses play fundamental roles in infection by binding to cell receptors, promoting cell fusion processes, or interacting with elements of the host immune system [11], [15], [16], [32].
In addition, S100β protein participates in the regulation of cell morphology by interacting with elements of the cytoplasmatic cytoskeleton.
Instead, some TACC1 isoforms have evolved a related, but distinct function by directly interacting with elements of the RNA splicing and transport machinery [ 19].
The SV protein or protein domain will eventually find itself in an endoplasmic reticulum export site (ERES), either by random diffusion or by interacting with elements stabilized in these areas, for example coat proteins involved in ER-to-Golgi ER-to-Golgi ER-to-Golgi
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During a recent visit to Washington, a Nintendo representative showed off a game in which the gadget's camera placed her in the game as she shook her head and waved her arms to interact with elements on the screen.
Agonist-dependent internalization of G protein-coupled receptors via clathrin-coated pits is dependent on the adaptor protein beta-arrestin, which interacts with elements of the endocytic machinery such as AP2 and clathrin.
In one scenario, the domain might interact with elements of the nuclear envelope that hinder the progression of the protein in the nuclear pore.
In both structures, the 3' ends of loop 3 terminate in the decoding center of the A site where they may interact with elements of the decoding groove.
This suggests that IAPP subsequences on the surfaces of gp5βf-based scaffolds specifically interact with elements of the parent IAPP sequence relevant to formation of toxic species.
The N-terminus of protomer A of a symmetry related molecule (indicated by a *) interacts with elements of the light-state dimer interface, which slightly affects the relative positioning of the two protomers.
One of these isoforms, TACC1S is localized exclusively to the cytoplasm [ 19], suggesting that the shorter isoforms would not be able to interact with elements of the chomatin remodeling and/or RNA processing machinery in the nucleus.
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CEO of Professional Science Editing for Scientists @ prosciediting.com