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However when father and mother's education were entered together as an interacting variable in the multivariate model, the interaction term in the model found having both father and mother with low education level at much higher risk of poor sexual health knowledge (OR 10.87; 95% CI 2.44 48.38).
If there was evidence for interaction, regression coefficients in all strata of the interacting variable were calculated using the Stata Lincom procedure.
Figures 6, 7, and 8 depict the surface and contour plots of each interacting variable with two variables kept constant and the other two varying within experimental range.
Each interacting variable in the data set contributes approximately one single unit step.
However, it will be difficult to retrieve the 'pure' slope coefficients for each factor as this will depend on the values of another variable (i.e. the interacting variable).
Cultural preference might be a confounding factor, or otherwise could be an interacting variable, in the association between region, residence or economic status and ANC use.
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Three chemometric approaches were applied: (i) factorial design (33 applied to surface plot and 23 applied to effect factor) for screening the potential interacting variables, (ii) univariant for optimizing insignificantly interacting variables and (iii) simplex for optimizing potentially interacting variables.
Thus, the above mentioned three interactions were assessed but only as two-factor interactions, and one interaction at a time with categorical characterization of the interacting variables.
However, since the statistical power of interaction analyses is generally low, the effects of interacting variables on outcomes are presented only as directions rather than graphically or by numbers.
HRs for alcohol categories across levels of interacting variables were computed as linear combinations of main effects and interactions.
After the interacting variables had been identified we proceeded to assess two-way interactions by repeating the above process.
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