Sentence examples for interacting targets from inspiring English sources

Here, m for a query ligand is the number of its interacting targets.

DYRK1A and GSK-3 (glycogen synthase kinase-3) were confirmed as interacting targets by Western blotting in various mouse tissues.

This contrasts with the three other methods used in [15 17] which are less suitable when working on multiple interacting targets.

Many drugs from a wide range of therapeutic areas have more than one interacting targets, and the multiple on-target and off-target bindings are essential for their efficacy and side effects.

Here we report the synthesis and biological characterization of 16-mercaptohexadecylphosphocholine, a thiol analog of MT which was designed to facilitate the search of MT interacting targets within the parasite by a variety of analytical methods.

To deal with many-to-one or one-to-many data associations, Park et al. [29] propose a general formulation called binary integer programming to handle a min-cost data association problem among target-measurement data associations through one-to-one, many-to-one, and one-to-many data associations (also called multi-way data associations) to track multiple interacting targets in video frames.

Particularly, the high ranking of hERG as a potential interacting target of a query compound may serve as a hERG toxicity alert for further safety investigation.

Ligand-based in silico target fishing can be used to identify the potential interacting target of bioactive ligands, which is useful for understanding the polypharmacology and safety profile of existing drugs.

In PhIN, one of two criteria, compounds criteria or scaffolds criteria, is used to define an interacting target pair.

✓This study addressed applications of an interacting target network, which was generated by shared compounds or a scaffold of a target pair for polypharmacology.

✓This study reports a Web-based tool that provides an interacting target network within or across human pathways, between human and virus, virus and virus, using a user-defined target-pair interaction.