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Based on these interaction data, our statistical analyses recaptured the fore-mentioned miRNA-mRNA interacting pattern, i.e., no miRNAs targeted over- or under-represented genes in either up- or down-regulated gene set.
Our results have further shown a particular interacting pattern of default mode network that can be characterized as both afferent and efferent influences on the medial prefrontal cortex and posterior cingulate cortex.
(1) A node is randomly selected (A) and is duplicated to generate a new node (A'), having the same interacting pattern as node A. (2) Each of the links to node A' is removed with a probability α (completely asymmetric divergence [44]).
The probability is defined to be 0 when 1 + σk is lower than 0. The interacting pattern of node A' is identical to that of node A. (2) For a divergence process, two different models were examined: the asymmetric divergence [ 14] and the symmetric divergence.
We can see that the similarity between the pocket of HDAC7 and the AChE is not determined by the pocket shape, but by their interacting pattern with only the probe molecules, namely the AD drugs and the HDAC inhibitors.
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Here we examined whether the interacting patterns of domains could affect their evolution.
Repetition of interacting patterns is crucial for learning languages, mathematics, science, music and the performing arts.
Large-scale climate change is superimposed on interacting patterns of climate variability that fluctuate on numerous temporal and spatial scales elements of which, such as seasonal timing, may have important impacts on local and regional ecosystem forcing.
Given a symmetric distance (or a covariance) matrix between individuals, the dimension-reduction methodologies, such as multidimensional scaling (MDS) and principal components analysis (PCA), can display individual interacting patterns effectively by means of two, or more, major eigenvector components [11].
In the PIN evolution, gene duplication is thought to be responsible for preferential attachment, because gene duplication creates a new node having the same interacting patterns as the original node, and a high-degree node is more likely to gain a new link by the duplication of a randomly selected node than a low-degree node [6].
We note that the 4C-Seq aimsoach aims to take a snapshot of chromatin interacting patterns, which reflect the average state across hundreds of thousands of cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com