Conversely, ectopic overexpression of several related TNFR superfamily members in HeLa cells did not lead to their interaction with Trx1, yet CD30 strongly interacted on the same cells under the same conditions.
Since the group-conserved H/D residue is four residues distant the highly conserved aspartate within TMD V, the two residues will interact on the same face of the α-helix.
In this study we examined the hypothesis that drugs that share the same therapeutic effect also share a common therapeutic mechanism by targeting not only known drug targets, but also by interacting unexpectedly on the same cryptic targets.
We focused on two contrasts (dominant vs subordinate foundresses, and dominant vs subordinate workers) because these contrasts represented females that were interacting together on the same nest and were not confounded by comparisons across castes.
Images taken in different years and on different continents interact on the same wall; a woman in China stares at the funeral in the Congo from within her own frame.
The combination of our genome-wide ChIP-PET data and the ChIP qPCR validation therefore suggest that PPARγ and RXR interact on the same DNA binding sites throughout the genome though of differing intensities.
To identify α or β structures, we simply need to calculate as follows: 1) the ratio of interacting amino acids to the total number of amino acids of the interface; 2) the number of amino acids separating two amino acids of the same segment, interacting with the same residue on the complementary segment.
All tRNAs adopt similar structures because they all have to interact with the same sites on the ribosome.
All approved PIs are competitive active-site inhibitors, and as such, would ideally mimic the enzyme substrate ensuring it interacts with the same residues on protease.
The film throws a revealing light on communism and capitalism, idealism and opportunism, art and commerce, and how they have interacted and operated on the same materials during the past half century.
