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Toward this end, we incorporated these unidirectional interactions into our hierarchical organization of interacting modules.
Evolutionary thinking in support of protein interaction analysis can reveal the conservation and diversification of interacting modules in cellular pathways.
To address such limitations, we adopted a mixture modeling procedure to construct a probabilistic genetic interaction network and then implemented a Bayesian approach to identify densely interacting modules in the probabilistic network.
The interconnected systems are modeled as dynamically interacting modules.
Reflecting this, the book presents the techniques and technology that enable mobility in a series of interacting modules.
Combined use of alternative P14 and L5b-P6 interacting modules provided robust orthogonality to the P5/ΔP5 assembly interface of the bimolecular complex.
Similar(15)
The deletion of this domain in chimpanzee PKC (ENSPTRP00000000076) implies that the recruitment of diacylglycerol might be achieved by an external interacting module.
Therefore, we considered the possibility that the assembly of a PVRL4-PVRL1 interacting module on the interface of two neighboring cells may be triggering lateral recruitment and/or activation of cell surface-localized proteins, which, in turn, conveys a prosurvival signal.
On the other hand, AMAP1 has multiple protein-interacting modules and can directly interact with different proteins, including protein kinase D2 (PRKD2) and cortactin.
Residues between 1,189 and 1,326 of ATRX serve as the dominant binding module for DAXX, and residues 321 865 of ATRX may constitute a secondary DAXX-interacting module (Tang et al., 2004).
These results support the notion that FDPL is part of a novel clathrin-interacting module.
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