We regard knowledge about tropical diseases and their social aetiology as a pre-requisite to act on and react to internationally and globally interacting links between diseases and their social determinants.
These studies have led to several major conclusions: (1) Hub proteins, that is, proteins that have many interacting links, tend to be more conserved [ 18, 24, 25].
Through genome-wide linkage scans using an F2 intercross population from TH and B6 strains, we identified multiple QTLs and interacting loci linked to hyperlipidemia, hyperglycemia, and obesity phenotypes.
These results indicate that Shroom3 and Dvl2 may interact to link PCP signaling to actomyosin contractility during neural tube morphogenesis.
Here, we show how, on a higher level, two scaffold proteins functionally interact to link two signaling modules.
Due to its unique biophysical properties, HA contributes directly to tissue homeostasis, interacts with link proteins and proteoglycans (PGs) thus maintaining the structural integrity of extracellular and pericellular matrices, and its interaction with cell surface HA receptors mediates crucial influences of HA on cell behavior.
Societies are becoming increasingly systemic, which means that different parts and institutions are constantly interacting and forming links.
Fibrinogen gamma chains are involved in fibrin polymerization and cross-linking, interacting with platelets and mediating thrombin binding to fibrin [ 32].
Using special tags added to links within emails, ClickTale is able to generate video and data on each individual user that clicked a link and consequently interacted with the linked website.
Aggrecans fill the interstices of the collagen meshwork by forming large aggregated complexes interacting with hyaluronan and link proteins.
