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All the interacting sites within ±1 Mb range of a positively interacting site were clustered as an enriched interacting domain.
All mutations affected the FBXW7 target interacting domain.
Interestingly, SMRT is recruited to PPARγ via its C-terminal interacting domain, and mutation of the proximal interacting domain does not interfere with recruitment via PPARγ.
MED25 interacts with VP16 through a central MED25 PTOV (Prostate tumour overexpressed)/ACID (Activator interacting domain) domain of unknown structure.
Most of these variants occurred within the RPGR interacting domain.
First, in definitions "by structure", the extensions are assigned to the interacting domain, by structure.
Similar(23)
PSI mutants lacking the U1 snRNP-interacting domain (PSIΔAB mutant) exhibit extended but futile mating attempts.
Bisgrove, D. A., Mahmoudi, T., Henklein, P. & Verdin, E. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.
Bisgrove, D.A., Mahmoudi, T., Henklein, P. & Verdin, E. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.
This site has been termed the alpha-interacting domain (AID), and is located 22 amino acids (a.a).
The amino-acid sequence of DivIVA does not show an apparent membrane-interacting domain.
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CEO of Professional Science Editing for Scientists @ prosciediting.com