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Since the available knowledge about protein-protein interactions is incomplete and contains many false positives, a major limitation common to all interaction networks is the quality of the interacting data used.
Section 2 describes the task of predicting PPIs between HIV-1 and human proteins and the available interacting data set in more details.
BiomarCaRE comprises two closely interacting data centres: one centre that is responsible for the analyses of all population-derived biomarkers which is based at the National Institute for Health and Welfare THLL) in Helsinki Finlandd.
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The LNs represent the infrastructures equipped with IWC modules like RFID readers, infrared receivers, Bluetooth receivers and WiFi access points which can interact data with PTs and afford the internal spatial characteristic about the PTs.
The correlations between the genetic variants were estimated from the EPIC-InterAct data.
To assess the validity of the genetic variants as instrumental variables, we tested the association of the variants with a range of covariates in the EPIC-InterAct data.
In this section, we apply the linear and localized IV methods to the EPIC-InterAct data set for the cardiovascular risk factors previously listed.
The EPIC-InterAct data also indicated an inverse association between root vegetables and diabetes risk (RR 0.87 [95% CI 0.77 0.99]); however, this association was not evident in two other studies in the meta-analysis that examined this vegetable subgroup (32, 33).
Moreover, in protein purification experiments performed in parallel, we always observed co-purification with YciR of proteins that by mass spectrometry were identified as MlrA and YdaM, which also indicated that these proteins do interact (data not shown).
Extending this simulation to 200 ns did not result in a complete dissociation of the helices, as a number of residues, e.g., R, R, S, F, or V, continued to interact (data not shown).
The visual representation is realized as interactive data chart which allows user to interact with data and explore variables.
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