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The interacting area between GTS1 and L19e is very close to that of Nop16 and GTS1 interacting area.
However, Diva shows the same interacting surface for both Hrk_ΔTM and Hrk_medium, suggesting that factors other than those pertinent to intermolecular interactions within the interacting area are playing a role in binding.
This suggests that the interacting area include the HER2-binding surface of ZHER2.
The interacting area, expressed in terms of BSA upon complex formation, ranges from 808 Å to 3370 Å.
The shift in the former subunit and the disorder in the latter resulted in the loss of the interacting area in the holo dimer.
In this crystal, there were the biological contact (COMP: 0.151, area: 400.4 Å) and crystal-packing contact (COMP: 0.087, area: 620.1 Å), and the biological contact may be biologically relevant in spite of the smaller interacting area, according to the primary citation where the authors describe that the active sites exist near the biological contact as shown in Figure 5b.
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The results of these experiments demonstrate that the TIP-1 specific antibody share or overlap with the HVGGSSV peptide for a common interacting areas within the TIP-1 protein.
The unusually large interacting surface area between the two domains may contribute to thermostability of the enzyme.
Using an energy systems diagram, the spatial unit model consists of three interacting subsystems – natural area, agricultural area and urban area – representing a simplified entity or unit model of each grid element within a city-region.
During this time, the city dominated much of the Maya region politically, economically, and militarily, while interacting with areas throughout Mesoamerica such as the great metropolis of Teotihuacan in the distant Valley of Mexico.
Evaluation of this organization has revealed that large-scale brain networks consist of multiple segregated subnetworks of interacting brain areas.
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