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These systems do not interact with environment, but with humans.
Such decision making engines would probably need to interact with environment to test the candidates and confirm their performance.
Most interesting, this genetic variant interacts with whether a person experienced abuse or neglect in their childhood, demonstrating that genes interact with environment.
All these things we learned by relying on our sensorium to inform our mind and tell us how to physically interact with environment.
Thus, CYP2D6 genotypes are not the only genetic factors that interact with environment in determining the susceptibility to HNSCC.
Another explanation is that there are other modifier genes on autosomes that interact with environment to result in different clinical symptoms.
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Real brains live inside bodies and interact with environments.
The senses are not things that got passively written on, but rather things that interact with environments.
Since they can interact with environments (e.g., carrying objects), control strategies need to deal with non-stationary dynamics.
The ability to learn behaviors, interact with environments, and construct niches (Laland et al. 2008; Gissis and Jablonka 2011) are three further mechanisms introduced below.
With advancing technology, it is possible to interact with environments and contexts in new and unexpected ways, redefining our notion of what is manmade.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com