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This diversity between highly homologous receptors that potentially interact with common ligands may result from higher order receptor complexes, interactions with membrane proteins or unique intracellular signaling intermediates.
Do the proteins interact with common metabolic pathways?
Phosphorylated R-Smads dissociate from the receptor and interact with common mediator Smad4 [ 153].
This can explain the similarity in biochemical properties and secondary structure elements among proteins that interact with common chaperones.
Factors bound to these sequences often interact with common coactivators, which, in turn, recruit the basal transcription machinery [ 57, 58].
It is possible that these demethylases interact with common as well as distinct genomic loci to repress transgenerational aging.
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Members of this group are serine/threonine protein kinases that are likely to play a conserved role in viral infection by interacting with common host cellular and viral factors; however, along with a conserved role, individual kinases may have unique functions in the context of viral infection in such a way that they are only partially replaceable even by close homologues.
While suppressing speech, the government also took advantage of Chinese Internet users' affinity for social media to polish Xi Jinping's image and post photos of him interacting with common citizens in everyday situations.
The ICC provided the government functionaries a platform where they interacted with "common women" in an informal environment and they knew the worth of their "information products".
19 Evidence has also shown that anemia interacts with common co-morbidities to synergistically increase the risk of outcomes such as frailty and mortality.
2Apart from the classical view of TFs interacting with promoter regions, TFs could activate gene expression by interacting with common lineage-specific TFs and/or binding to distal regions (enhancers).
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