Sentence examples for interact to impair from inspiring English sources

Thus the present data suggest the presence of several processes which contribute and possibly interact to impair diaphragm muscle contractile function in type 1 diabetes, several of which are potentially amenable to therapeutic interventions.

First, these small diffusible molecules can interact with DNA and RNA to impair cell function.

The activity of DPP4 seems to be increased in patients with T2DM and there are a fair number of in vitro and in vivo studies demonstrating that this enzyme is able to interact with proinflammatory pathways and to impair endothelial function through incretin-dependent and independent mechanisms, potentially providing a new link between T2DM and atherosclerosis.

Analyses reveal that statistical power is primarily a nonlinear function of network effect size and network size (N), although both of these factors can interact with network density and network structure to impair power under certain rare conditions.

At the postsynaptic membrane, eAβOs interact with glutamate receptors and dysregulate calcium influx to impair long-term potentiation (LTP) and enhance long-term depression (LTD) [ 3– 6].

The current study illustrates that individual, family-specific and systemic issues interact to facilitate or impair mental health care utilization.

Strikingly, MeCP2 does not interact with the SIRT1 mutant H363Y, in which a single amino acid is converted in order to impair its deacetylase enzymatic activity.

Coupled with increased rates of polypharmacy often observed among these age groups, it is also likely that these factors interact to contribute to and compound impaired levels of cognition; which is directly associated with increased falls occurrence and future falls risk.

LMB is thought to function primarily as an inhibitor of the export of proteins from the nucleus to the cytoplasm because of its ability to interact with and impair the function of the nuclear export factor crm-1 (Kudo et al, 1999).

Rosemary: Being part of WFI'S team accorded me an opportunity to interact with hearing impaired girls.

The mutant huntingtin can interact with p62, impairing its ability to recognize cargo aggregates and organelles.