Exact(6)
Cells within a tissue continuously interact to coordinate normal tissue functions and maintain homeostasis.
Although the brain and the fat body are both capable of acting as sensors for nutritional conditions, their individual contributions to growth regulation are poorly understood, as are the mechanisms by which the signals they produce might interact to coordinate growth.
Here, we use mathematical modeling and perturbation experiments to address how the feedback loops within the PKD-CERT network interact to coordinate ceramide transport.
A comprehensive picture, however, of the PRC2 complex and the manner in which its different components interact to coordinate the regulated methyl-transferase activity remains elusive.
A major question relating to ovarian development is how the FOXL2 and R-SPO1/Wnt4 pathways interact to coordinate ovarian development.
How the two major signal transduction system activated by IGF-I receptor/IGF-I, the PI3-K/Act pathway and the Raf/Ras/MAPK cascade interact to coordinate the activity of IGF-I in the mammary epithelia is still largely an unanswered question, but the two signaling pathways appear to have extensive interactions with each other [ 58, 59].
Similar(54)
However, it is not clear how these generators interact in order to coordinate with each other when several different muscles are involved in a specific behaviour, or when a particular muscle is involved in several different behaviours.
However, given that the reductive nature of rickettsial genomes may result in high levels of constitutively expressed loci and reduced operons, and that many antitoxins contain motifs common to two, three and even four different DNA-binding-proteins [162], incomplete and noncontiguous rickettsial TA modules may still interact with one another to coordinate a response to stress within host cells.
As both mTORC1 and FoxO1 integrate nutrient and growth factor signals, it is conceivable that they interact with each other to coordinate cellular responses to nutrient availability.
Recently, it has been shown that distal-less (DLX 2 homeobox transcription factor and EGFR signaling interacts at multiple levels to coordinate neurogenesis and proliferation in the postnatal SVZ by promoting the lineage transition from NSCs to TAPs [42].
The existence of these protein complexes also raises the interesting possibilities that, in proliferating cells, condensins interact with chromatin-remodeling complexes to coordinate cell-cycle progression and/or transcriptional regulation to changes in global chromosome compaction states.
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