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Having established that Rab7a interacts directly with vimentin we checked, using co-immunoprecipitation and pull-down, the ability to interact of the different Rab7a mutant proteins with vimentin.
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The aim of our reconstruction is to present the first integrated network reconstruction of how these four key protein kinases interact, with annotations of the different interactions according to the current knowledge, and further evaluate the role of this interaction network in global metabolic regulation.
Overall, a better understanding of the way in which the varied actions of AMPK interact with the different metabolic requirements of cancer cells is clearly essential to allow the more rational design of clinical trials of metformin and other AMPK-modulating drugs.
These cells span the thickness of the retina, and appear well placed to interact with all of the different types of neuron in the retina.
From the X-ray structure, the side chains in each turn of helix αC interact with the different domains of the enzyme.
A variety of proteins specifically interact with the different sub-domains of the enzymes and direct their wide range of cellular functions.
Translation initiation in eukaryotes requires the interplay of at least 10 initiation factors that interact at the different steps of this phase of gene expression.
The estrogen appears to interact with the different types of estrogen receptors in all types of tissues in both men and women.
New models of how different drugs (cisapride, dofetilide and lidocaine [lignocaine]) interact with the different states of the channels have been developed.
Nonetheless, to succeed in exploiting such 3D structural conformations, it is of significance that initially the cells introduced permeate and interact within the different depths of the scaffold profile.
Of the 34 differentially expressed secreted protein genes associated with the biotrophic phase, 11 were glycoside hydrolases from six families of hydrolases, which enables M. roreri to interact with the different biochemical components of plant cell walls.
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CEO of Professional Science Editing for Scientists @ prosciediting.com