The main difference with the algorithm proposed in this article is the lack of an interacting model, which limits its ability to handle object interactions.
The second model (the interacting model) simultaneously fitted age, sex, 22 main effects, 22 SNP-sex interactions, and 220 epistatic interactions.
Its following and interacting model is a cross between Facebook and Twitter.
The case with interaction presents an increased complexity, and a deep analysis will be the subject of a future work (in[31] we present some results on a toy interacting model).
Hence, our results with a. a. substitutions fit the proposed TLR2-Pam2CSK4 interacting model.
The interacting model reduced deviance and AIC and thus improved the model fit to the data.
Under the interacting model, the effect for rs11861531a, but not that for rs11641468a, was still significant.
Predicted probabilities were estimated using parameters from the fully interacted model.
The main-effect model detected rs9927163 with a marginally significant dominance effect, which was also present in the interacting model.
The association of rs12934561 with risk for ALI, which was not significant under the main-effect model, became significant under the interacting model.
