the local 3D graphs which are composed of the ligand and the interacting residues for each individual molecular ensemble.
Most parallelisation schemes split the set of particles (left { x_{t}^{ k)} right }_{1 le k le K}) into subsets and then run separate (but possibly interacting) PFs for each subset.
To perform a global comparative analysis among autoimmune and neurodegenerative genetic interactomes, we derived a list of interacting partners for each gwas-geneset (Table 2, Table S3).
The complete identification of all known shelterin components as well as identification of known interacting partners for each bait protein lends validity to our approach.
Analyzing the interacting partners for each protein in HypoxiaDB, it was found that 215 proteins have their 75% interacting partners within HypoxiaDB itself.
Lists of specifically interacting clones for each screen that are not provided in this manuscript in Additional files 1 through 5 can be requested from the corresponding author.
A literature mining tool (EVEX) (Van Landeghem et al. 2011) was then used to retrieve information about gene regulation and interacting networks, for each homologous gene described in public databases.
To further narrow-down and refine this list, we obtained a list of all known interacting genes for each of the known and candidate genes using the Human Reference Protein Database (HRPD [ 15].
Statistical analysis identified 65 and 82 enriched inter-chromosomal interacting regions for each replicate data generated from the enzyme approach, with about 40% overlap of the identified regions (30 regions) between the two biological replicates.
Using the same datasets as Figure 5A, interacting proteins for each moonlighting or non-moonlighting proteins in the datasets are clustered based on their functional similarity using the funsim score (Eqn. 4).
Does your family even like each other enough to interact for two or more consecutive hours?
