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41 Docking studies on this class of biphenyl-based AIs into a homology model of human aromatase (PDB code: 1TQA) revealed that the cyano group might interact favourably with Ser478 of the active site through hydrogen bond interactions.
All the apoproteins, like phospholipids, are amphipathic and interact favourably with both lipids and water.
The partial charges so formed behave just like those of a permanently polar molecule and interact favourably with their counterparts in the polar molecule that originally induced them.
Although the latter continuously flickers from one direction to another (with an average of zero dipole overall), the induced dipole follows it, and the two correlated dipoles interact favourably with one another and cohere.
The temperature was also observed to interact favourably with the flow rate, presenting a method of increasing the particle yield and relative crystallinity, with little change in average particle size or particle size distribution.
Preliminary multiple molecular dynamics simulations (10 1-ns-long simulations) suggested that two of such analogues, F3A and F4H (structures shown in Figure 1), might be able to interact favourably with the active site of BoNTAe.
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As a consequence, a ligand that interacts favourably with the outer water (e.g. BDP5290) should favour binding to MRCKβ over ROCK1.
The structure shows that the inhibitor interacts favourably with the enzyme in subsite S4.
Australian Journal of Mechanical Engineering 2004 1 63 71], strongly suggests that SAPL has the ability to decrease friction in prosthetic joints by acting as a boundary lubricant, and that SAPL interacts favourably with PyC.
The PIP2 molecules interacted favourably and extensively with the positively charged residues of the JM, and in particular with the R645 R647 cationic cluster, in good agreement with the experimental studies of Michailidis et al. [16].
HDIs have been shown to favourably interact with other treatment regimen, such as ionising radiation or chemotherapy [ 10].
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