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Outlines the primary and secondary client needs that OH aims to target, or the organisational areas of need, as defined in OH's Strategic Intent; Treatment.
After applying curative intent treatment for clinically localized PCa with surgery or radiotherapy, 15-30% of patients show biochemical progression (Cher et al., 1998), which precedes a clinically detectable recurrence at the pelvis or metastatic disease within a period of months or years (Moul et al., 2000; Roberts et al., 2001).
The cornerstone of curative intent treatment is surgery with negative margins.
The study population presented a persistent mortality after curative intent treatment.
Definitive chemoradiation (dCRT) is considered curative intent treatment for patients with inoperable or irresectable esophageal cancer.
Also, chemotherapeutics or the Epstein-Barr virus targeted therapies can be used when curative intent treatment is not feasible anymore.
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These palliative intent treatments fall beyond the scope of this article and will be discussed only briefly.
Most patients are diagnosed with advanced-stage tumors, precluding curative-intent treatment.
Low usage levels for laboratory and radiology are consistent with the intent of exclusion of curative-intent treatment for hospice patients.
In this regard, Wang et al. [26] followed up 245 patients with NPC who received curative-intent treatment with plasma EBV DNA concentration every 3 to 6 months.
Therefore, high-dose radiotherapy combined with chemotherapy has long been the mainstay of therapy modalities and is a primary component of curative-intent treatment for nondisseminated NPC [9], [39].
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