Exact(8)
This possible abnormal activity of energy generation can be related to the fact that melanoma (and also other cancers) is intensively positive in positron emission tomography (PET) scans due to their intense demand for energy, where tumor has up-regulated receptors that take in glucose and subsequently have high levels of glycolysis.
The canals of Hering are strongly and intensively positive for EpCAM (and cytokeratin 19).
Interestingly, those intensively positive cells, but not vaguely positive cells, were also immune-positive for the HC-related markers myosin6, Brn3c, and α9AchR.
As the immune-histochemical staining has been negative for CK20 and intensively positive for CK7, a carcinoma from gastrointestinal origin was excluded [ 7, 8].
Endothelial cells were also intensively positive for tyrosine p-STAT-3 and served as an internal positive control in the negative cases.
As the expression of Brn3c is Math1 dependent, it is conceivable that markers of HC cells were expressed in a restricted manner in cells intensively positive for Math1.
Similar(51)
Considering only thin melanomas (<1 mm thickness), one out of 14 cases was intensively MCAM/MUC18 positive (UPN13).
These eased controls require that EU member states, as a minimum, intensively monitor positive flocks through testing of fallen stock and animals leaving the flock for slaughter, but with movement restrictions limited to export interdiction [ 18].
Primary tumours and LMs were intensively L1-positive and weakly CAECAM1-positive.
Double staining with the ED2 antibody showed that the intensively LPL-positive cells were Kupffer cells.
Our results showed that the bacterial-sensing Tlr4 was more variable than the viral-sensing Tlr7, and that Tlr4 evolution was more intensively shaped by positive selection than in Tlr7.
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