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In our experience the far from brilliant results obtained led us to change our follow-up in 2006 and make it less intensive, tailoring it to the stage of the disease, the reliability of the diagnostic methods, times of recurrences and no less important, the age of patients.
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However, unlike the DPP, the LLDPP intervention was less intensive, tailored to literacy needs and cultural preferences, and delivered in Spanish.
It is plausible that some highly vulnerable patients could benefit from more resource-intensive tailored prevention packages; stratification of risk would make realisation of such interventions in clinical practice more feasible.
This is particularly crucial for the most vulnerable and disadvantaged children, who we know can thrive with intensive and tailored support.
More intensive and tailored interventions are likely to be more effective.
Feedback can range from simple advice to more intensive or tailored information [ 14].
Such patients could be reasonable subjects for more intensive or tailored treatment, including immunomodulatory therapy (Pages et al, 2010).
This study showed that intensive interventions tailored to the needs of low-income Latinos can result in clinically important short-term improvements in glucose control and glucose variability.
More intensive or tailored quitline programs may need to be developed among callers with MHCs as their quit rates appear to be lower than callers without MHCs.
The trial finding the greatest effect was of an intensive intervention (tailored written information with a reinforcing newsletter at 12 months plus two telephone counselling sessions) primarily aiming to increase breast screening uptake.
However, recent research has suggested that adolescents with elevated psychopathic traits are not "untreatable" and that they can improve with intensive interventions tailored to their unique emotional, cognitive, and motivational styles [ 13].
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CEO of Professional Science Editing for Scientists @ prosciediting.com