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Regardless, rapid diagnosis and continuing public health control of the current outbreak in Haiti as well as future outbreaks is paramount for limiting sickness and death, and intensive studies using a variety of basic science, diagnostic, and epidemiologic tools will remain useful for reducing the overall global impact of cholera.
In utero electroporation (IUE) is a simple and rapid approach to in vivo investigate exogenous gene function in mouse brain, and intensive studies using IUE have greatly contributed to analyze the characterization of specific steps during mouse brain development.
Intensive studies using the model have been conducted, including studies on the effects of neutral wind on EPB evolution (Huba et al. 2009; Krall et al. 2009; Huba and Krall 2013), the decay phase of EPBs (Krall et al. 2010a, b), and the electrostatic reconnection process of merging EPBs (Huba et al. 2015).
More recently, intensive studies using in vivo genetic lineage-tracing approaches have provided new insights into the nature of cellular identity and plasticity in the liver and suggested that adult liver cells can flexibly respond to injury by actively converting their own cell fate to other cell fates (Fan et al. 2012; Sekiya & Suzuki 2012, 2014; Michelotti et al. 2013; Yanger et al. 2013).
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To date only one HRV strain, HRV-QPM, has been a deliberate target for intensive study using molecular tools [ 25].
No major population stratification between KORA Southwestt Germany) and two other cohorts from Northern Germany could be detected in an intensive study using a genomic control approach [ 12].
Currently, intensive pilot studies using autonomous infrared-triggered remote video cameras are conducted in Loango National Park, Gabon [48] and Taï National Park, Côte d'Ivoire [49].
Initial studies using intensive alkylator regimens with optional incorporation of autologous stem cell transplant (ASCT) suggested a survival benefit.
To date, scant empirical data are available on the influence of these factors on reactivity, leading to suggestions that uniform procedures should be used routinely by researchers to assess and report reactivity in studies using intensive longitudinal methods (for further details, see Barta et al. 2012).
Overall, we can conclude that by providing direct instruction to teachers regarding language stimulation techniques, the program shows preliminary results indicating favorable outcomes for the expressive language of children, as has been found in other studies using more intensive curriculum interventions (e.g., Justice et al. 2008).
In keeping with studies using computationally intensive individual-based models, we concluded that, for the purposes of limiting spread, prevention was better than cure [2], [3].
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