More intensive management significantly increased species differences in average height, stand basal area and total volume.
The paradox is partly resolved by the further finding that the intensive strategy significantly changed the relationship between A1C and risk of death (interaction P < 0.0007).
Although several commercial products in this field are available, such as "3Shape," their user interactions are intensive and significantly influence the accuracy of results.
Only when the results of all intervention trials were pooled (9– 11), it was possible to conclude that intensive control significantly reduces coronary events without an increased risk of death.
Our analysis suggests that the introduction of a liaison nurse post within intensive care significantly reduced the length of delays in the discharge process despite an increase in patient turnover.
Intensive treatment significantly reduced macrosomia and related problems at the time of delivery but had no effect on overweight and obesity at 5 years of age; both groups were more obese than the background population (22).
Since the Steno-2 study showed that intensive therapy significantly reduced the risk of retinopathy by about 60% in type-2 diabetes patients with MAU [ 20], it seems justified an intensive therapy to control glucose more tight than in those without retinopathy.
In the Steno-2 study, a multifactorial approach of intensive treatment significantly reduced microvascular complications (including diabetic nephropathy and retinopathy) already after a mean monitoring period of 3.8 years [ 44], whereas the number of macrovascular events was significantly reduced after 13.3 years [ 45].
74, 75 In an ancillary study of the Epidemiology of Diabetes Intervention and Complication Study (EDIC), 76 a period of intensive therapy significantly reduced the prevalence of ED among men suffering from diabetes for 10 years or more and microvascular complications, compared with those with a 1- to 5-year history of disease, but without complications.
The total score of the Generic Scales and the Cancer Scale in the non-intensive phase were significantly better than in the intensive-phase, in both patient self-reports as well as proxy-reports.
